Currently running with uBlock Origin with a lot of filter lists and Consent-o-matic, and the hidden setting to auto decline cookie dialogs but still getting popups, sticky videos and such.
Used to go with I still don’t care about cookies but heard it can default to accepting more cookies than needed
I also use SponsorBlock for YouTube, which skips sponsor segments in YouTube videos (and optionally other kinds of segments like intros, self promos, etc.) it’s crowd-sourced for identifying the segments but for almost all the videos I watch someone has already marked at least the sponsor segments