Erin Fox, associate chief pharmacy officer of University of Utah Health, told CBS MoneyWatch, that most of the drugs in short supply are generic, older products, and around half are injectable drugs that require more stringent manufacturing processes.

There are myriad reasons for the hundreds of drug shortages now facing doctors and patients, many of which remain unclear. But, as Ars has reported before, the root cause of shortages of low-cost, off-patent generic drugs is well established. These drugs have razor-thin to non-existent profit margins, driven by middle managers who have, in recent years, pushed down wholesale prices to rock-bottom levels. In some cases, generic manufacturers lose money on the drugs, disincentivizing other players in the pharmaceutical industry from stepping in to bolster fragile supply chains. Several generic manufacturers have filed for bankruptcy recently.

  • pelespirit@sh.itjust.worksOP
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    7 months ago

    This sounds more like market manipulation to me, because pharma has shown that they’re capable of anything to make money. I hope they’re getting looked at.

    But, as Ars has reported before, the root cause of shortages of low-cost, off-patent generic drugs is well established. These drugs have razor-thin to non-existent profit margins, driven by middle managers who have, in recent years, pushed down wholesale prices to rock-bottom levels.

  • Stillhart@lemm.ee
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    7 months ago

    I have cancer. It’s SUPER fun having to deal with drug shortages every fucking month, let me tell you. Nothing makes a cancer patient feel better than having to call around to local pharmacies to see who can fill a painkiller prescription. And you can’t call for a refill even a single day before your current scrip is out. So they can’t have it ready for you or set it aside. You run out and then you have to fucking FIGHT to not have to deal with withdrawal on top of the pain. EVERY. SINGLE. MONTH.

    But you know, profits are more important than health care. So I get it. Can’t have CEO’s going hungry just because I’m in a little pain.

    • mctoasterson@reddthat.com
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      7 months ago

      This makes me seethe with anger. The current regulations are not preventing abuse of medications, it is hurting people with cancer, psychiatric conditions, and a whole host of other serious illnesses.

      We have somehow created a system where addicts and pushers can get plenty of supply but normal patients with legitimate pharmacological need can’t get their meds.

      • sugar_in_your_tea@sh.itjust.works
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        7 months ago

        My proposed solution is a mixture of removing those regulations, legalizing more recreational drugs, and improving funding for addiction recovery programs.

        People will use drugs recreationally regardless of legal status, it’s our choice as a society how we respond to that. I think making care available is better than locking people up and screwing over patients in the meantime…

    • pelespirit@sh.itjust.worksOP
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      7 months ago

      Dude, I don’t even know what to say. Our healthcare is broken and the people who can fix it are getting paid not to. I’m so angry for you.

  • Apytele@sh.itjust.works
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    7 months ago

    I saw the headline and just immediately knew its because the old generics don’t make enough money. My seroquel is like $1 for a 90 day supply. That new latuda shit is like $10… per pill.

  • AutoTL;DR@lemmings.worldB
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    7 months ago

    This is the best summary I could come up with:


    These drugs have razor-thin to non-existent profit margins, driven by middle managers who have, in recent years, pushed down wholesale prices to rock-bottom levels.

    In some cases, generic manufacturers lose money on the drugs, disincentivizing other players in the pharmaceutical industry from stepping in to bolster fragile supply chains.

    The ADHD drug Adderall, for instance, has been in critical shortage since October 2022, causing millions of patients around the country to struggle to fill their prescriptions.

    Although that problem has since been resolved, it came amid a significant increase in Adderall prescriptions, which spiked further during the pandemic when telehealth prescribing became more common.

    But, in a joint letter with the Food and Drug Administration last August, the DEA said that, by its data, manufacturers of amphetamine products (including Adderall) only sold approximately 70 percent of their allotted quotas in 2022.

    The organization has put forth policy recommendations to prevent shortages and improve supply chains, advocating for federal and regulatory changes.


    The original article contains 532 words, the summary contains 161 words. Saved 70%. I’m a bot and I’m open source!